Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962006 | 0.84 | HSD11B1 (0.57) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL3436309 | 0.82 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL2155243 | 0.81 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL2961026 | 0.81 | CHRM4 (0.62) | ALDH1A1SMN1; SMN2KMT2AHSD11B1LMNA | |
| SCHEMBL17308412 | 0.81 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL28396664 | 0.80 | ADRB1 (0.71) | ALDH1A1HTTLMNAKDM4EADRB1 | |
| SCHEMBL15935176 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL19171088 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL14328390 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL3207920 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPSR1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548798-A1 | Antiviral agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |