Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911893 | 0.89 | GPR35 (0.53) | TSHRRAB9ANPC1MEN1KMT2A | |
| Nitrophenolate SCHEMBL27532826 | 0.84 | GPR35 (0.63) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL29051225 | 0.84 | GPR35 (0.63) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL28297600 | 0.82 | GPR35 (0.57) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL10540580 | 0.82 | GPR35 (0.57) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL7643816 | 0.82 | GPR35 (0.61) | TSHRRAB9ANPC1MEN1KMT2A | |
| Nitrophenolate SCHEMBL26026 | 0.82 | GPR35 (0.65) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL28029048 | 0.82 | GPR35 (0.65) | TSHRMEN1KMT2AGPR35TDP1 | |
| Nitrophenolate SCHEMBL29360402 | 0.82 | GPR35 (0.65) | TSHRMEN1KMT2AGPR35TDP1 | |
| SCHEMBL22898040 | 0.81 | ALDH1A1 (0.53) | TSHRRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526093-A1 | New non-steroidal agents as 5-alpha reductase inhibitors | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |