Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CD4 | P01730 | 2/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566488 | 0.85 | CYP2D6 (0.48) | CYP2D6CYP3A4CYP2C9CYP2C19TSHR | |
| SCHEMBL20521052 | 0.79 | CYP2D6 (0.41) | LMNAPOLBALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL8573781 | 0.77 | CYP2D6 (0.46) | LMNAPOLBALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL14166152 | 0.77 | SMN1; SMN2 (0.56) | LMNAPOLBALDH1A1CD4SORT1 | |
| SCHEMBL8540877 | 0.75 | HTR6 (0.54) | LMNAPOLBALDH1A1CD4SORT1 | |
| SCHEMBL8540875 | 0.75 | HTR6 (0.54) | LMNAPOLBALDH1A1CD4SORT1 | |
| SCHEMBL1474768 | 0.74 | SMN1; SMN2 (0.48) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1474765 | 0.74 | SMN1; SMN2 (0.48) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1474769 | 0.74 | SMN1; SMN2 (0.48) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL1476146 | 0.74 | SMN1; SMN2 (0.48) | LMNAPOLBALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | claimed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |