Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822915 | 0.88 | DHFR (0.60) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL6977364 | 0.84 | DHFR (1.00) | DHFRMAOBRAB9AMAOANPC1 | |
| SCHEMBL22139476 | 0.81 | PTGS1 (0.67) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL15383157 | 0.81 | DHFR (0.68) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL7379345 | 0.79 | PRMT5 (0.59) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL7379441 | 0.79 | LMNA (0.59) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL4302609 | 0.79 | MAOB (0.53) | DHFRMAOBGAARAB9ASMN1; SMN2 | |
| SCHEMBL197017 | 0.78 | LMNA (0.72) | MAOBGAARAB9ASMN1; SMN2MAPT | |
| SCHEMBL15383385 | 0.78 | DHFR (0.64) | DHFRRAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5045790 | 0.78 | MAOB (0.89) | MAOBGAARAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |