Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 10/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566545 | 0.83 | RECQL (0.56) | DHFRPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL9566435 | 0.82 | MGAM (0.54) | POLBAGPAT2NPC1TSHRRAB9A | |
| SCHEMBL4291022 | 0.81 | AGPAT2 (0.52) | AGPAT2 | |
| SCHEMBL11612156 | 0.80 | KDM4E (0.50) | DHFRPIK3CAPOLBTSHR | |
| SCHEMBL13957870 | 0.76 | KDM4E (0.46) | POLB | |
| SCHEMBL29684606 | 0.76 | KDM4E (0.46) | POLB | |
| SCHEMBL30030889 | 0.75 | DHFR (0.43) | DHFRPOLBNPC1TSHRRAB9A | |
| SCHEMBL29168726 | 0.75 | DHFR (0.43) | DHFRPOLBNPC1TSHRRAB9A | |
| SCHEMBL31053304 | 0.73 | FBP1 (0.44) | NPC1TSHRRAB9A | |
| SCHEMBL1516692 | 0.73 | FBP1 (0.44) | NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |