Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527255 | 0.90 | GPR84 (0.46) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL2533535 | 0.90 | GPR84 (0.46) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL2532461 | 0.87 | GPR84 (0.42) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL11598362 | 0.84 | HAO1 (0.55) | GPR84FFAR1FFAR4HAO1ALDH1A1 | |
| SCHEMBL13160784 | 0.82 | GPR84 (0.57) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL1946353 | 0.82 | HAO1 (0.52) | GPR84FFAR1FFAR4HAO1ALDH1A1 | |
| SCHEMBL2527134 | 0.81 | ALDH1A1 (0.42) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL410371 | 0.79 | HAO1 (0.44) | FFAR1SMN1; SMN2HAO1ALDH1A1TDP1 | |
| SCHEMBL25303773 | 0.78 | GPR84 (0.52) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL1924519 | 0.78 | ALDH1A1 (0.53) | FFAR1SMN1; SMN2ALDH1A1TDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536105-A1 | Ruthenium(II)-binap diketonate complexes | MONSANTO COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5144050-A | Hydrogenation Catalysts | MONSANTO COMPANY (US) | 1992-09-01 | — | — | US | disclosed |