SCHEMBL9566732

SCHEMBL9566732

CC(=O)OCc1nc(C(C)(C)O)c(C(=O)O)[nH]1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7878657 0.85 ALDH1A1 (0.40) ALDH1A1
SCHEMBL27334875 0.72 GAA (0.33)
SCHEMBL7883597 0.71 ALDH1A1 (0.41) ALDH1A1
SCHEMBL7883248 0.70 GRM1 (0.37) ALDH1A1
SCHEMBL987234 0.67 ALDH1A1 (0.42) ALDH1A1
SCHEMBL7298547 0.65 ALDH1A1 (0.40) ALDH1A1
SCHEMBL2626707 0.65 GLA (0.31)
SCHEMBL8861128 0.64 ALDH1A1 (0.40) ALDH1A1
SCHEMBL1969215 0.63 CYP3A4 (0.34) ALDH1A1
SCHEMBL9673902 0.61 MAPT (0.63) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573218-A2 4-Carboxyimidazoles as angiotensin II antagonists and their thrapeutic use SANKYO COMPANY LIMITED (JP) 1993-12-08 EP disclosed