Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566853 | 0.87 | CYSLTR2 (0.32) | FFAR1MAPTKMT2AACACB | |
| SCHEMBL9566773 | 0.85 | MAPT (0.30) | MAPTKMT2A | |
| SCHEMBL9566840 | 0.82 | KDM4E (0.34) | ALDH1A1MAPT | |
| SCHEMBL9566772 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AACACB | |
| SCHEMBL11375563 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL3300820 | 0.74 | PDE3B (0.42) | ALDH1A1FFAR1MAPTACACB | |
| SCHEMBL1059319 | 0.73 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL8170006 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2A | |
| SCHEMBL9263293 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AACACB | |
| SCHEMBL17941801 | 0.70 | APP (0.45) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |