Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566752 | 0.87 | ALDH1A1 (0.32) | MAPTKMT2AACACBFFAR1 | |
| SCHEMBL9566773 | 0.84 | MAPT (0.30) | MAPTKMT2A | |
| SCHEMBL9515539 | 0.76 | KMT2A (0.37) | MAPTKMT2AACACBFFAR1CCNC | |
| SCHEMBL9566840 | 0.70 | KDM4E (0.34) | MAPT | |
| SCHEMBL9199754 | 0.70 | ACACB (0.40) | MAPTKMT2AACACBTHRA | |
| SCHEMBL9566735 | 0.68 | LNPEP (0.31) | — | |
| SCHEMBL28366145 | 0.66 | ICAM1 (0.39) | MAPTKMT2AFFAR1 | |
| SCHEMBL9518131 | 0.66 | AOC3 (0.39) | MAPTKMT2AACACBCCNCCDK8 | |
| SCHEMBL9566772 | 0.65 | ALDH1A1 (0.38) | KMT2AACACB | |
| SCHEMBL18961357 | 0.65 | MAPT (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |