Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566735 | 0.85 | LNPEP (0.31) | LNPEP | |
| SCHEMBL9566752 | 0.82 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL2464513 | 0.79 | KDM4E (0.48) | KDM4EMAPTLNPEPALDH1A1 | |
| SCHEMBL9814691 | 0.74 | NOS1 (0.53) | KDM4EMAPTALDH1A1 | |
| SCHEMBL9566886 | 0.72 | MEN1 (0.41) | KDM4EMAPTALDH1A1 | |
| SCHEMBL9566853 | 0.70 | CYSLTR2 (0.32) | MAPT | |
| SCHEMBL11369806 | 0.70 | GCK (0.49) | KDM4ELNPEPALDH1A1 | |
| SCHEMBL9566773 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL17019021 | 0.69 | ALDH1A1 (0.43) | KDM4EMAPTLNPEPALDH1A1 | |
| SCHEMBL509101 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |