Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566791 | 0.86 | P4HTM (0.62) | P4HTMMAPTALDH1A1RAB9AMCL1 | |
| SCHEMBL9566788 | 0.84 | P4HTM (0.59) | P4HTMMAPTALDH1A1RAB9AMCL1 | |
| SCHEMBL9566812 | 0.84 | P4HTM (0.59) | P4HTMMAPTALDH1A1RAB9AMCL1 | |
| SCHEMBL30828577 | 0.83 | P4HTM (0.72) | P4HTMMAPTALDH1A1RAB9AMCL1 | |
| SCHEMBL30828579 | 0.83 | P4HTM (0.72) | P4HTMMAPTALDH1A1RAB9AMCL1 | |
| SCHEMBL9566833 | 0.82 | P4HTM (0.63) | P4HTMALDH1A1KMT2ACXCR1CXCR2 | |
| SCHEMBL9566835 | 0.82 | P4HTM (0.63) | P4HTMMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL9566802 | 0.81 | NPC1 (0.67) | P4HTMMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL9566803 | 0.81 | P4HTM (0.66) | P4HTMMAPTALDH1A1RAB9ALMNA | |
| SCHEMBL9566887 | 0.80 | P4HTM (0.69) | P4HTMMAPTALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |