Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566887 | 0.88 | P4HTM (0.69) | P4HTMNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9566852 | 0.83 | P4HTM (0.55) | P4HTMALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL9566790 | 0.83 | LMNA (0.59) | P4HTMNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9566862 | 0.82 | ABL1 (0.51) | P4HTMSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9566835 | 0.82 | P4HTM (0.63) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9566833 | 0.82 | P4HTM (0.63) | P4HTMALDH1A1CYP1A2KMT2ACYP3A4 | |
| SCHEMBL9566802 | 0.81 | NPC1 (0.67) | P4HTMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9566776 | 0.81 | P4HTM (0.66) | P4HTMNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2302302 | 0.81 | RAB9A (0.72) | P4HTMNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL9518006 | 0.80 | P4HTM (0.67) | P4HTMKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |