Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 16/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 15/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566883 | 0.94 | CXCR2 (0.52) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566759 | 0.88 | CXCR2 (0.55) | CXCR2CXCR1P4HTMALDH1A1NPC1 | |
| SCHEMBL9566792 | 0.88 | P4HTM (0.55) | P4HTMALDH1A1NPC1RAB9A | |
| SCHEMBL9566902 | 0.87 | CXCR2 (0.62) | CXCR2CXCR1P4HTMALDH1A1NPC1 | |
| SCHEMBL9566758 | 0.87 | NPC1 (0.57) | CXCR2CXCR1P4HTMALDH1A1NPC1 | |
| SCHEMBL9566849 | 0.85 | P4HTM (0.63) | P4HTMALDH1A1NPC1RAB9A | |
| SCHEMBL9566788 | 0.85 | P4HTM (0.59) | CXCR2CXCR1P4HTMALDH1A1NPC1 | |
| SCHEMBL9566868 | 0.85 | CXCR2 (0.60) | CXCR2CXCR1P4HTMALDH1A1NPC1 | |
| SCHEMBL9566814 | 0.84 | P4HTM (0.47) | CXCR2P4HTMNPC1RAB9A | |
| SCHEMBL9566843 | 0.82 | TRPV1 (0.54) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |