Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566825 | 0.88 | P4HTM (0.66) | P4HTMNPC1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9566897 | 0.88 | P4HTM (0.66) | P4HTMNPC1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9566884 | 0.88 | SMN1; SMN2 (0.55) | P4HTMALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL9566814 | 0.86 | P4HTM (0.47) | P4HTMNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9566777 | 0.86 | P4HTM (0.61) | P4HTMNPC1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL9566786 | 0.85 | CXCR2 (0.57) | P4HTMNPC1ALDH1A1RAB9A | |
| SCHEMBL9566792 | 0.85 | P4HTM (0.55) | P4HTMNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL9566883 | 0.85 | CXCR2 (0.52) | P4HTMALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9566758 | 0.85 | NPC1 (0.57) | P4HTMNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL9566887 | 0.85 | P4HTM (0.69) | P4HTMNPC1CYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |