Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 13/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 11/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566786 | 0.94 | CXCR2 (0.57) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566811 | 0.89 | CXCR2 (0.57) | CXCR2CXCR1P4HTMF2PLG | |
| SCHEMBL9566753 | 0.87 | CXCR2 (0.54) | CXCR2CXCR1P4HTMF2PLG | |
| SCHEMBL9566799 | 0.86 | CXCR2 (0.53) | CXCR2CXCR1P4HTMMEN1LMNA | |
| SCHEMBL9566849 | 0.85 | P4HTM (0.63) | P4HTMALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9566852 | 0.85 | P4HTM (0.55) | CXCR2CXCR1P4HTMF2PLG | |
| SCHEMBL9566814 | 0.83 | P4HTM (0.47) | CXCR2P4HTMMEN1LMNAKMT2A | |
| SCHEMBL9566759 | 0.83 | CXCR2 (0.55) | CXCR2CXCR1P4HTMALDH1A1 | |
| SCHEMBL9566792 | 0.82 | P4HTM (0.55) | P4HTMALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL9566758 | 0.82 | NPC1 (0.57) | CXCR2CXCR1P4HTMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |