Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566775 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2MGLLRAB9ATAAR1NPC1 | |
| SCHEMBL27667176 | 0.78 | MAPT (0.38) | NPC1GAABCHEFAAH | |
| SCHEMBL9566847 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2 | |
| SCHEMBL26093046 | 0.76 | KMT2A (0.41) | SMN1; SMN2 | |
| SCHEMBL13577783 | 0.72 | SMN1; SMN2 (0.69) | SMN1; SMN2MGLLRAB9ATAAR1NPC1 | |
| SCHEMBL11065587 | 0.72 | SMN1; SMN2 (0.69) | SMN1; SMN2MGLLRAB9ATAAR1NPC1 | |
| SCHEMBL5568443 | 0.72 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1GAABCHE | |
| SCHEMBL2243907 | 0.72 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ATAAR1NPC1GAA | |
| SCHEMBL9566819 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL1416481 | 0.69 | SMN1; SMN2 (0.59) | SMN1; SMN2MGLLRAB9ATAAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |