SCHEMBL9566847

SCHEMBL9566847

O=C(NCCO)Oc1ccnc(CO)c1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566819 0.92 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL9566810 0.86 LOXL2 (0.41) SMN1; SMN2
SCHEMBL9566743 0.84 ALDH1A1 (0.44)
SCHEMBL9566906 0.81 SPHK2 (0.45) SMN1; SMN2EPHX1
SCHEMBL9566774 0.79 SMN1; SMN2 (0.39) SMN1; SMN2
SCHEMBL9566767 0.78 NOS3 (0.38)
SCHEMBL9566800 0.78 SMN1; SMN2 (0.52) SMN1; SMN2
SCHEMBL9519673 0.77 NOS3 (0.41)
SCHEMBL28292630 0.76 MEN1 (0.48)
SCHEMBL9566834 0.75 LOXL2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0533130-A1 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-24 EP disclosed