Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 10/20 | 0.58 |
| ▸ | CXCR1 | P25024 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566738 | 0.95 | CXCR2 (0.64) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566756 | 0.87 | RAB9A (0.57) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9519589 | 0.86 | CXCR2 (0.54) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566753 | 0.86 | CXCR2 (0.54) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566799 | 0.85 | CXCR2 (0.53) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566861 | 0.85 | P4HTM (0.61) | MEN1KMT2ALMNARAB9ANPC1 | |
| SCHEMBL9566871 | 0.84 | RAB9A (0.53) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566811 | 0.84 | CXCR2 (0.57) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL9566848 | 0.84 | P4HTM (0.55) | CXCR2CXCR1MEN1KMT2ARXFP1 | |
| SCHEMBL12020864 | 0.83 | MEN1 (0.70) | CXCR2CXCR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |