Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566756 | 0.92 | RAB9A (0.57) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9566738 | 0.88 | CXCR2 (0.64) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566789 | 0.88 | P4HTM (0.60) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL12020925 | 0.86 | P4HTM (0.57) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9566837 | 0.85 | P4HTM (0.58) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9566861 | 0.85 | P4HTM (0.61) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9566769 | 0.84 | KDM4E (0.57) | P4HTMRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9566764 | 0.84 | TRPV1 (0.60) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL9566829 | 0.84 | CXCR2 (0.58) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566871 | 0.83 | RAB9A (0.53) | P4HTMRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |