Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566855 | 0.90 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566787 | 0.86 | P4HTM (0.53) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566861 | 0.86 | P4HTM (0.61) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566756 | 0.86 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566738 | 0.85 | CXCR2 (0.64) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL9566829 | 0.84 | CXCR2 (0.58) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9517172 | 0.84 | BCL2L1 (0.50) | P4HTMSCN9A | |
| SCHEMBL9566891 | 0.84 | P4HTM (0.49) | NPC1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9566848 | 0.83 | P4HTM (0.55) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9566862 | 0.82 | ABL1 (0.51) | SMN1; SMN2MEN1KMT2ALMNAP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |