Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566897 | 0.90 | P4HTM (0.66) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9566787 | 0.89 | P4HTM (0.53) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9566861 | 0.89 | P4HTM (0.61) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9566796 | 0.89 | LMNA (0.56) | P4HTMALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9566849 | 0.88 | P4HTM (0.63) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9566769 | 0.88 | KDM4E (0.57) | P4HTMNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL9566868 | 0.88 | CXCR2 (0.60) | P4HTMNPC1ALDH1A1RAB9A | |
| SCHEMBL9566753 | 0.87 | CXCR2 (0.54) | P4HTMALDH1A1RAB9AKMT2ALMNA | |
| SCHEMBL9566737 | 0.87 | NPC1 (0.57) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9566887 | 0.87 | P4HTM (0.69) | P4HTMNPC1ALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |