Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 11/20 | 0.42 |
| ▸ | CA2 | P00918 | 11/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 8/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982625 | 0.93 | CA1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL1962748 | 0.93 | CA1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL12955914 | 0.93 | CA1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL31272586 | 0.93 | CA1 (0.47) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16415818 | 0.91 | CA2 (0.46) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL13030026 | 0.91 | LMNA (0.46) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16759507 | 0.86 | CYP3A4 (0.46) | LMNATSHRALDH1A1CA1CA2 | |
| SCHEMBL28069731 | 0.86 | CYP3A4 (0.46) | LMNATSHRALDH1A1CA1CA2 | |
| SCHEMBL28272444 | 0.86 | CYP3A4 (0.46) | LMNATSHRALDH1A1CA1CA2 | |
| SCHEMBL10803892 | 0.85 | CA1 (0.57) | LMNATSHRKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562185-A1 | 3-(Arylmethyl)-1-(3'-diethylaminopropyl) pyrrolidines and process of preparation thereof | Council of Scientific and Industrial Research (IN) | 1993-09-29 | — | — | EP | disclosed |