SCHEMBL9567014

SCHEMBL9567014

O=S(=O)(O)CCN1CCNCC1O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
TSHR P16473 1/20 0.31
GABRG2 P18507 1/20 0.31
NFKB1 P19838 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRA6 Q16445 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25229426 0.81
SCHEMBL62392 0.80 CA1 (0.35)
SCHEMBL510150 0.79 LMNA (0.31) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL1701174 0.79 TAAR1 (0.34)
SCHEMBL83681 0.78 CA1 (0.44)
SCHEMBL1139996 0.76 TDP1 (0.36)
SCHEMBL25232214 0.76 OPRM1 (0.32) LMNACYP3A4GABRA1TSHRGABRG2
SCHEMBL27824766 0.75
Hydrochloric Acid SCHEMBL27700512 0.74 AGL (0.33)
SCHEMBL17477707 0.74 GBA1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1213303-C Action for neutrlizing polycation in chromatography equipment of whole blood EBERT CORP (US) 2005-08-03 CN disclosed
CN-1495428-A Action for neutrlizing polycation in chromatography equipment of whole blood ���Ͽع����޹�˾ 2004-05-12 CN disclosed
CN-1125343-C Chromatographic device and method using polyanion neutralization polycation action ABBOTT LAB (US) 2003-10-22 CN disclosed
CN-1285918-A Neutralization of polycations in chromatographic apparatus for whole blood ABBOTT LAB (US) 2001-02-28 CN disclosed
EP-0568338-A2 Methods for the use of spermidine/spermine N'-acetyltransferase as a progonostic indicator and/or a tumor response marker HEALTH RESEARCH, INC. (US) 1993-11-03 EP disclosed