Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350427 | 0.90 | NOTUM (0.40) | TSHRHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22745804 | 0.86 | MAPT (0.36) | HPGDALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9423183 | 0.86 | ALDH1A1 (0.36) | TSHRHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9468954 | 0.86 | MAPT (0.35) | HPGDALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9423295 | 0.84 | POLB (0.32) | TSHRHPGDMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9495057 | 0.83 | HPGD (0.30) | HPGDMAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10575883 | 0.83 | HSP90AA1 (0.32) | MAPTCYP1A2CYP2C9KMT2A | |
| SCHEMBL31468720 | 0.82 | TSHR (0.34) | TSHRHPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9519865 | 0.81 | PPOX (0.35) | HPGDMAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL19827391 | 0.81 | SCN9A (0.39) | POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | claimed |
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |