Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468954 | 0.91 | MAPT (0.35) | PPOXSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL9523001 | 0.87 | PPOX (0.33) | PPOXDHODHSMN1; SMN2HPGDMAPT | |
| SCHEMBL9586969 | 0.84 | ALDH1A1 (0.32) | SMN1; SMN2HPGDMAPTLMNACYP1A2 | |
| SCHEMBL9521255 | 0.84 | HPGD (0.37) | PPOXSMN1; SMN2HPGDMAPTKMT2A | |
| SCHEMBL22745804 | 0.83 | MAPT (0.36) | SMN1; SMN2HPGDMAPTLMNACYP1A2 | |
| SCHEMBL9521382 | 0.83 | MAPT (0.38) | PPOXSMN1; SMN2HPGDMAPTKMT2A | |
| SCHEMBL9522986 | 0.83 | MAPT (0.38) | PPOXSMN1; SMN2HPGDMAPTKMT2A | |
| SCHEMBL9521057 | 0.82 | GAA (0.38) | PPOXSMN1; SMN2HPGDMAPTLMNA | |
| SCHEMBL9567022 | 0.81 | TSHR (0.35) | SMN1; SMN2HPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL9350427 | 0.79 | NOTUM (0.40) | SMN1; SMN2HPGDMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |