SCHEMBL9567136

SCHEMBL9567136

C=CCON(C=O)CC(=C)[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567243 0.84 UCHL1 (0.32) UCHL1
SCHEMBL9595516 0.84 UCHL1 (0.32) UCHL1
SCHEMBL9567241 0.84 UCHL1 (0.32) UCHL1
SCHEMBL9137762 0.83
SCHEMBL9567135 0.80 ABCB1 (0.32)
SCHEMBL9567154 0.79 NR1H2 (0.36) UCHL1
SCHEMBL9595744 0.79 NR1H2 (0.36) UCHL1
SCHEMBL9596289 0.74 MMP2 (0.33)
SCHEMBL9567175 0.74 MMP2 (0.33)
SCHEMBL8108240 0.73 CHRM2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993001192-A1 2-(2-SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-01-21 WO disclosed
EP-0522504-A1 2-(2-substituted pyrrolidinylthio)-carbapenem derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1993-01-13 EP disclosed