SCHEMBL9567489

SCHEMBL9567489

Fc1ccc(/C=C/c2cc[nH]c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 8/20 0.52
PTGS1 P23219 2/20 0.45
APP P05067 1/20 0.45
HSD11B1 P28845 1/20 0.42
NQO2 P16083 1/20 0.41
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41
FBP1 P09467 1/20 0.39
TNFRSF1A P19438 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567491 1.00 NFE2L2 (0.52) NFE2L2PTGS1APPHSD11B1NQO2
SCHEMBL2459029 0.83 ALDH1A1 (0.39)
SCHEMBL2459032 0.83 ALDH1A1 (0.39)
SCHEMBL9567521 0.78 NFE2L2 (0.50) NFE2L2PTGS1ALOX5PTGS2FBP1
SCHEMBL9567576 0.78 RAB9A (0.44)
SCHEMBL9567524 0.78 NFE2L2 (0.50) NFE2L2PTGS1ALOX5PTGS2FBP1
SCHEMBL9567577 0.78 RAB9A (0.44)
SCHEMBL9567534 0.78 AHR (0.50) NFE2L2PTGS1ALOX5PTGS2FBP1
SCHEMBL9567531 0.78 AHR (0.50) NFE2L2PTGS1ALOX5PTGS2FBP1
SCHEMBL22468800 0.78 NFE2L2 (0.78) NFE2L2PTGS1APPHSD11B1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575923-A1 Triazole Derivatives Ikeda Mohando Co., Ltd. (JP) 1993-12-29 EP disclosed