Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034023 | 0.83 | RIPK1 (0.45) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL13151737 | 0.83 | MEN1 (0.50) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL13401414 | 0.73 | CYP2C19 (0.40) | RIPK1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13596171 | 0.73 | MEN1 (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL22095153 | 0.73 | CYP2C19 (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL28434224 | 0.72 | RIPK1 (0.44) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL20475967 | 0.71 | LMNA (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL1697396 | 0.71 | LMNA (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL9397678 | 0.71 | RIPK1 (0.46) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL10420406 | 0.71 | RIPK1 (0.43) | RIPK1KMT2AMEN1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522547-A2 | Carbonyl-containing degradable chelants, uses and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |