Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567685 | 1.00 | LMNA (0.51) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL9254151 | 0.84 | MAPT (0.55) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL9254147 | 0.84 | MAPT (0.55) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL5597287 | 0.78 | TP53 (0.61) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL11319464 | 0.78 | LMNA (0.49) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL11319459 | 0.78 | LMNA (0.49) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL7273129 | 0.76 | MEN1 (0.54) | LMNAMEN1MAPTKMT2AAKR1C3 | |
| SCHEMBL2812585 | 0.74 | MAPT (0.85) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL5613678 | 0.74 | LMNA (0.51) | LMNANPSR1MEN1S1PR4MAPT | |
| SCHEMBL4218085 | 0.74 | LMNA (0.51) | LMNANPSR1MEN1S1PR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561664-A1 | Process for the preparation of 4-pyrimidines | SYNTHELABO (FR) | 1993-09-22 | — | — | EP | disclosed |