Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 13/20 | 0.57 |
| ▸ | PLAU | P00749 | 9/20 | 0.57 |
| ▸ | F10 | P00742 | 8/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9432197 | 0.98 | PLAU (0.58) | F9PLAUF10HPRT1F2 | |
| SCHEMBL28537323 | 0.85 | LIMK1 (0.48) | F9PLAUF10 | |
| SCHEMBL30583137 | 0.78 | F9 (0.65) | F9PLAUF10 | |
| SCHEMBL563279 | 0.78 | F9 (0.65) | F9PLAUF10 | |
| Hydrochloric Acid SCHEMBL9402488 | 0.77 | F9 (0.66) | F9PLAUF10 | |
| Hydrochloric Acid SCHEMBL9431489 | 0.76 | KDM4E (0.54) | F9PLAUF10HPRT1F2 | |
| SCHEMBL9431295 | 0.74 | ALDH1A1 (0.60) | — | |
| SCHEMBL17934651 | 0.74 | ALDH1A1 (0.48) | HPRT1 | |
| SCHEMBL13709504 | 0.74 | F9 (0.68) | F9PLAUF10F2PLG | |
| Hydrochloric Acid SCHEMBL9432183 | 0.74 | F9 (0.62) | F9PLAUF10F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |