Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 10/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 6/20 | 0.54 |
| ▸ | PLAU | P00749 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583137 | 1.00 | F9 (0.65) | F9BCL2L1SLC9A1HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL9402488 | 0.98 | F9 (0.66) | F9BCL2L1SLC9A1HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL9431252 | 0.83 | F9 (0.70) | F9F10 | |
| Hydrochloric Acid SCHEMBL9432183 | 0.83 | F9 (0.62) | F9HDAC6F10PLAUCFD | |
| SCHEMBL13116539 | 0.82 | BCL2L1 (0.60) | F9BCL2L1SLC9A1HDAC6HDAC3 | |
| SCHEMBL12820023 | 0.80 | BCL2L1 (0.58) | F9BCL2L1SLC9A1HDAC6HDAC3 | |
| SCHEMBL29366392 | 0.80 | BCL2L1 (0.69) | BCL2L1SLC9A1HDAC6HDAC3HDAC4 | |
| SCHEMBL347544 | 0.80 | BCL2L1 (0.69) | BCL2L1SLC9A1HDAC6HDAC3HDAC4 | |
| SCHEMBL13709460 | 0.79 | F9 (0.77) | F9HDAC6F10PLAUCFD | |
| SCHEMBL13709463 | 0.79 | F9 (1.00) | F9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691859-B2 | Broad spectrum antibacterial compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2014-04-08 | — | — | US | claimed |
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | BAVARI SINA | 2011-04-14 | — | — | US | claimed |
| US-20090221564-A1 | Heterocyclic Compounds and Their Use in the Treatment of Cardiovascular Disease | TRIGEN LIMITED (GB) | 2009-09-03 | — | — | US | claimed |
| EP-1991220-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASE | TRIGEN LIMITED (GB) | 2008-11-19 | — | — | EP | claimed |
| WO-2007096362-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASE | TRIGEN LIMITED (GB) | 2007-08-30 | — | — | WO | claimed |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2007-05-17 | — | — | US | claimed |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ARMY, UNITED STATES | 2007-05-17 | — | — | US | claimed |
| EP-0482717-B1 | Use of a benzo[b]thiophene-2-carboximidamide derivative against heart failure | AKZO NOBEL NV (NL) | 1994-06-08 | — | — | EP | claimed |
| US-5276052-A | For treatment of heart failure | AKZO N.V. (NL) | 1994-01-04 | — | — | US | claimed |
| EP-0482717-A1 | Use of a benzo[b]thiophene-2-carboximidamide derivative against heart failure | Akzo Nobel N.V. (NL) | 1992-04-29 | — | — | EP | claimed |
| EP-4680343-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192415-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-09-19 | — | — | WO | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-5276052-A | For treatment of heart failure | AKZO N.V. (NL) | 1994-01-04 | — | — | US | disclosed |
| US-5276052-A | For treatment of heart failure | AKZO N.V. (NL) | 1994-01-04 | — | — | US | disclosed |
| EP-0482717-A1 | Use of a benzo[b]thiophene-2-carboximidamide derivative against heart failure | Akzo Nobel N.V. (NL) | 1992-04-29 | — | — | EP | disclosed |
| EP-0482717-A1 | Use of a benzo[b]thiophene-2-carboximidamide derivative against heart failure | Akzo Nobel N.V. (NL) | 1992-04-29 | — | — | EP | disclosed |
| EP-0482717-A1 | Use of a benzo[b]thiophene-2-carboximidamide derivative against heart failure | Akzo Nobel N.V. (NL) | 1992-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221564-A1 | Heterocyclic Compounds and Their Use in the Treatment of Cardiovascular Disease | F12, F5, F3 | F9 5/4885BCL2L1 2447/4885SLC9A1 1287/4885 |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | MPO, CAT, LPO | F9 3649/4885BCL2L1 167/4885SLC9A1 3920/4885 |
| US-20070112049-A1 | nonpeptidic inhibitors of Botulinum neurotoxin A metalloprotease activity, such as 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-5-carboximidamide, used for treating, inhibiting or preventing intoxication caused by bacteria | ACHE, CTRL, MMP2 | F9 946/4885BCL2L1 1242/4885SLC9A1 4217/4885 |
| US-20110086877-A1 | Small Molecule Inhibitors of Botulinum Neurotoxins | ACHE, MMP2, TIMP3 | F9 861/4885BCL2L1 1290/4885SLC9A1 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.