Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568008 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9567963 | 0.85 | ALDH1A1 (0.44) | ALDH1A1HTTTRPV1KDM4CKDM5A | |
| SCHEMBL9048529 | 0.81 | PTGIR (0.66) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9568077 | 0.81 | TRPV1 (0.46) | ALDH1A1HTTTRPV1KDM4CKDM5A | |
| SCHEMBL9568034 | 0.80 | PSMB5 (0.57) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9568000 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TRPV1KDM4CKDM5AKDM5B | |
| SCHEMBL9568047 | 0.78 | TRPV1 (0.44) | ALDH1A1TRPV1KDM4CKDM5AKDM5B | |
| SCHEMBL9568037 | 0.78 | CNR1 (0.46) | ALDH1A1HTTTRPV1KDM4CKDM5A | |
| SCHEMBL9568029 | 0.77 | TAOK1 (0.49) | ALDH1A1TRPV1KDM4CKDM5AKDM5B | |
| SCHEMBL9568025 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HTTSMN1; SMN2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |