Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623941 | 0.83 | HTR6 (0.51) | HTTCYP19A1TBXAS1TRPV1PARP1 | |
| SCHEMBL9567967 | 0.82 | TRPV1 (0.44) | ALDH1A1XBP1HTTCYP19A1TBXAS1 | |
| SCHEMBL1566782 | 0.80 | SIGMAR1 (0.49) | ALDH1A1CYP19A1TBXAS1TRPV1PARP1 | |
| SCHEMBL9048482 | 0.80 | PTGIR (0.48) | PTGIRPARP1PARP2KDM4CHTR6 | |
| SCHEMBL10585088 | 0.79 | CYP19A1 (0.48) | ALDH1A1CYP19A1TBXAS1TRPV1PARP1 | |
| SCHEMBL29114059 | 0.78 | SIGMAR1 (0.50) | CYP19A1TBXAS1TRPV1PARP1PARP2 | |
| SCHEMBL30658590 | 0.78 | SIGMAR1 (0.50) | CYP19A1TBXAS1TRPV1PARP1PARP2 | |
| SCHEMBL8858400 | 0.77 | PTGIR (0.75) | PTGIRTBXAS1 | |
| SCHEMBL9048486 | 0.77 | PTGIR (0.55) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9053439 | 0.76 | PTGIR (0.54) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |