Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568132 | 1.00 | SCN1A (0.38) | SCN1ASCN2ASCN3ABMPR1BBMPR1A | |
| SCHEMBL9568234 | 0.91 | ALDH1A1 (0.43) | KDM1A | |
| SCHEMBL9568245 | 0.90 | F2 (0.41) | SCN1ASCN2ASCN3ABMPR1BBMPR1A | |
| SCHEMBL9568246 | 0.90 | F2 (0.41) | SCN1ASCN2ASCN3ABMPR1BBMPR1A | |
| SCHEMBL9568208 | 0.89 | SCN1A (0.44) | SCN1ASCN2ASCN3ABMPR1BBMPR1A | |
| SCHEMBL9568210 | 0.89 | SCN1A (0.44) | SCN1ASCN2ASCN3ABMPR1BBMPR1A | |
| SCHEMBL9568084 | 0.80 | F2 (0.46) | KDM1A | |
| SCHEMBL9568086 | 0.80 | F2 (0.46) | KDM1A | |
| Hydrochloric Acid SCHEMBL9568183 | 0.79 | F2 (0.46) | KDM1A | |
| SCHEMBL8410171 | 0.76 | CFTR (0.48) | CFTRKDM1AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |