Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568146 | 0.88 | YAP1 (0.43) | LMNAITGB3ITGA2BPOLBALDH1A1 | |
| SCHEMBL8407957 | 0.87 | POLB (0.43) | LMNAITGB3ITGA2BHRH3POLB | |
| SCHEMBL8410914 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BHRH3POLBALDH1A1 | |
| SCHEMBL9568089 | 0.83 | LMNA (0.41) | LMNAITGB3ITGA2BHRH3POLB | |
| SCHEMBL9568113 | 0.83 | PRSS1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL8407202 | 0.83 | YAP1 (0.49) | LMNAPOLBALDH1A1SMN1; SMN2YAP1 | |
| Hydrochloric Acid SCHEMBL9568117 | 0.82 | PRSS1 (0.46) | ITGB3ITGA2B | |
| SCHEMBL8407956 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BHRH3POLBALDH1A1 | |
| SCHEMBL8409563 | 0.80 | SMN1; SMN2 (0.49) | LMNAHRH3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9568130 | 0.80 | POLB (0.41) | LMNAITGB3ITGA2BHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |