Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169124 | 0.83 | TSHR (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29656610 | 0.83 | TSHR (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL27874688 | 0.81 | TDP1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Bromide SCHEMBL28214529 | 0.81 | HSD11B1 (0.45) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL1870627 | 0.81 | HSD11B1 (0.45) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Fluoride SCHEMBL27976646 | 0.81 | HSD11B1 (0.45) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| O-Xylene SCHEMBL11776221 | 0.79 | TSHR (0.56) | CYP3A4TSHRTDP1ALDH1A1GAA | |
| SCHEMBL27958458 | 0.77 | MEN1 (0.48) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8409006 | 0.76 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2127253 | 0.76 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564788-A2 | Sulfonylbenzyl substituted imidazopyridines as AII-antagonists | BAYER AG (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0562261-A2 | Sulphonylbenzyl substituted imidazoles | BAYER AG (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0557843-A2 | Sulfonylbenzyl-substituted pyridones as pharmaceuticals | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| EP-0557842-A2 | Sulphonylbenzyl substituted imidazolylpropenic acid derivatives | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |