Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568329 | 0.94 | MAPT (0.41) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568291 | 0.92 | MAPT (0.37) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568349 | 0.91 | MAPT (0.38) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568312 | 0.88 | TOP2A (0.41) | TOP2ATOP2B | |
| SCHEMBL9568386 | 0.87 | PRKCZ (0.39) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568309 | 0.85 | ALDH1A1 (0.39) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568315 | 0.84 | PRKCZ (0.40) | MAPTHPGDALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9568366 | 0.83 | MAPT (0.40) | MAPTHPGDALDH1A1TDP1GRM6 | |
| SCHEMBL9568343 | 0.81 | TOP2A (0.42) | LMNATOP2ATOP2B | |
| SCHEMBL9568342 | 0.80 | TOP1 (0.34) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |