Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568349 | 0.94 | MAPT (0.38) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568329 | 0.90 | MAPT (0.41) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568299 | 0.90 | MAPT (0.40) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568467 | 0.89 | GSK3B (0.36) | HPGDKDM4EPOLB | |
| SCHEMBL9568305 | 0.85 | MAPT (0.38) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568342 | 0.83 | TOP1 (0.34) | — | |
| SCHEMBL9568291 | 0.83 | MAPT (0.37) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568346 | 0.83 | TOP1 (0.40) | — | |
| SCHEMBL9568340 | 0.81 | MAPT (0.41) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL9568449 | 0.81 | PRKCZ (0.38) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |