Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | LSS | P48449 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9320345 | 0.99 | THRB (0.60) | THRBLSSTSHRMAPTALDH1A1 | |
| SCHEMBL9320194 | 0.88 | THRB (0.65) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9320433 | 0.87 | THRB (0.59) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9426171 | 0.86 | THRB (0.63) | THRBLSSMAPTALDH1A1KDM4E | |
| Dimethylamine SCHEMBL9320437 | 0.86 | THRB (0.63) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9320604 | 0.85 | THRB (0.68) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9513241 | 0.85 | THRB (0.82) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9321206 | 0.84 | THRB (0.64) | THRBLSSMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9426784 | 0.84 | THRB (0.67) | THRBLSSMAPTALDH1A1KDM4E | |
| SCHEMBL9319893 | 0.83 | THRB (0.65) | THRBLSSMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524146-A1 | Aminosubstituted Piperazinederivatives | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |