Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568302 | 0.93 | PRKCZ (0.41) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568345 | 0.92 | PRKCZ (0.42) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568296 | 0.91 | KDM4E (0.41) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568318 | 0.89 | ALDH1A1 (0.38) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568385 | 0.88 | LMNA (0.35) | LMNA | |
| SCHEMBL9568298 | 0.87 | LMNA (0.39) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568357 | 0.84 | PRKCZ (0.40) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568384 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9568294 | 0.83 | PRKCZ (0.43) | PRKCZKDM4EALDH1A1HPGDGAA | |
| SCHEMBL9568297 | 0.82 | KDM4E (0.45) | PRKCZKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |