Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872699 | 0.84 | ALDH1A1 (0.34) | HPGD | |
| SCHEMBL900006 | 0.81 | KMT2A (0.35) | HPGD | |
| SCHEMBL8443514 | 0.77 | HPGD (0.41) | HPGDCYP3A4RAB9A | |
| SCHEMBL10357774 | 0.77 | KCNH2 (0.39) | SCN5A | |
| SCHEMBL9029091 | 0.75 | NR3C1 (0.32) | SCN5A | |
| SCHEMBL9028592 | 0.75 | NR3C1 (0.32) | SCN5A | |
| SCHEMBL4208635 | 0.75 | ESR1 (0.39) | HPGDCYP3A4 | |
| SCHEMBL7071459 | 0.75 | TYR (0.44) | CYP3A4 | |
| SCHEMBL11458697 | 0.75 | TYR (0.44) | CYP3A4 | |
| SCHEMBL7604874 | 0.74 | IGF1R (0.36) | HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524146-A1 | Aminosubstituted Piperazinederivatives | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |