Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029091 | 1.00 | NR3C1 (0.32) | NR3C1PGRNR3C2SCN5A | |
| SCHEMBL7604874 | 0.78 | IGF1R (0.36) | — | |
| SCHEMBL4208635 | 0.76 | ESR1 (0.39) | NR3C1PGRNR3C2 | |
| SCHEMBL872699 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL9568441 | 0.75 | HPGD (0.31) | SCN5A | |
| SCHEMBL10650084 | 0.73 | LMNA (0.36) | NR3C1PGRNR3C2 | |
| SCHEMBL8443514 | 0.72 | HPGD (0.41) | — | |
| SCHEMBL10618792 | 0.71 | HPGD (0.33) | NR3C1PGRNR3C2 | |
| SCHEMBL1838149 | 0.71 | SRD5A1 (0.41) | — | |
| SCHEMBL8624118 | 0.71 | PTGS2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521422-B1 | Benzomorphanes and their use as pharmaceuticals | BOEHRINGER INGELHEIM KG (DE) | 1996-05-08 | — | — | EP | disclosed |
| EP-0521422-A1 | Benzomorphanes and their use as pharmaceuticals | BOEHRINGER INGELHEIM KG (DE) | 1993-01-07 | — | — | EP | disclosed |