Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568373 | 0.95 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568294 | 0.91 | PRKCZ (0.43) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568296 | 0.90 | KDM4E (0.41) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568345 | 0.90 | PRKCZ (0.42) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568315 | 0.90 | PRKCZ (0.40) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568384 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568318 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9568360 | 0.87 | LMNA (0.36) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9568344 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL9229230 | 0.85 | KDM4E (0.42) | ALDH1A1KDM4EGAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |