SCHEMBL9568599

SCHEMBL9568599

C=CC(=O)Oc1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.62
ALDH1A1 P00352 3/20 0.62
LMNA P02545 2/20 0.62
GAA P10253 1/20 0.62
ATM Q13315 1/20 0.60
PLAU P00749 5/20 0.59
HDAC1 Q13547 2/20 0.59
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
PLA2G7 Q13093 1/20 0.55
PKM P14618 1/20 0.54
PKLR P30613 1/20 0.54
AKR1C3 P42330 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568790 0.86 PGR (0.60) PGRSMN1; SMN2ALDH1A1LMNAHDAC1
SCHEMBL9568736 0.86 KMT2A (0.56) PGRSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL9568645 0.84 HDAC1 (0.62) PGRSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL3254798 0.84 SMN1; SMN2 (0.65) PGRSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL9568588 0.81 GFER (0.60) SMN1; SMN2ALDH1A1LMNAGAAHDAC1
SCHEMBL11580703 0.80 ALDH1A1 (0.56) SMN1; SMN2ALDH1A1GAAMEN1KMT2A
SCHEMBL9568821 0.80 PGR (0.53) PGRALDH1A1HDAC1MEN1KMT2A
SCHEMBL9568737 0.80 PGR (0.64) PGRALDH1A1HDAC1PKLRHTT
SCHEMBL398955 0.79 HDAC1 (0.57) PGRSMN1; SMN2ALDH1A1LMNAGAA
SCHEMBL8752432 0.79 PLAU (0.76) PGRSMN1; SMN2ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed