SCHEMBL9568645

SCHEMBL9568645

C=CC(=O)Nc1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.62
ALDH1A1 P00352 3/20 0.62
LMNA P02545 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
GAA P10253 1/20 0.62
ATM Q13315 1/20 0.60
GPR27 Q9NS67 1/20 0.58
PGR P06401 1/20 0.58
PLAU P00749 3/20 0.56
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PLA2G7 Q13093 1/20 0.55
PKM P14618 1/20 0.54
PKLR P30613 1/20 0.54
AKR1C3 P42330 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568497 0.95 LMNA (0.62) HDAC1ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9568656 0.89 AKR1C3 (0.60) HDAC1ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL3820009 0.85 TGM2 (0.67) HDAC1ALDH1A1SMN1; SMN2GAAGPR27
SCHEMBL9568599 0.84 PGR (0.65) HDAC1ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL398955 0.84 HDAC1 (0.57) HDAC1ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9568604 0.83 TGM2 (0.64) HDAC1ALDH1A1GAAMEN1KMT2A
SCHEMBL1380888 0.83 FYN (0.62) ALDH1A1LMNASMN1; SMN2GAAMEN1
SCHEMBL31162428 0.83 FYN (0.62) ALDH1A1LMNASMN1; SMN2GAAMEN1
SCHEMBL398954 0.81 SMN1; SMN2 (0.68) HDAC1ALDH1A1LMNASMN1; SMN2GAA
SCHEMBL14607474 0.80 L3MBTL1 (0.54) HDAC1ALDH1A1LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed