Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606129 | 0.79 | DRD2 (0.57) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL5167242 | 0.78 | HTR1A (0.89) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL5171727 | 0.78 | HTR1A (0.89) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL8169648 | 0.78 | HTR1A (1.00) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL5171731 | 0.78 | HTR1A (0.89) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL8169645 | 0.78 | HTR1A (1.00) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL5167251 | 0.78 | HTR1A (0.89) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL24029258 | 0.76 | DRD2 (0.54) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL14545524 | 0.76 | DRD2 (0.54) | HTR1ADRD2DRD3CHRM2CHRM1 | |
| SCHEMBL31324598 | 0.76 | DRD2 (0.73) | HTR1ADRD2DRD3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544240-A1 | Benzoquinoxalines and pharmaceutical compositions containing them | SANDOZ LTD. (CH) | 1993-06-02 | — | — | EP | disclosed |