SCHEMBL9568813

SCHEMBL9568813

O=C(O)c1csc(OC(F)F)n1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
PLA2G4A P47712 1/20 0.36
ACHE P22303 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36
HPGDS O60760 1/20 0.36
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GRM4 Q14833 1/20 0.35
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29911145 0.82 L3MBTL1 (0.45) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL9264657 0.78 RAB9A (0.56) ALDH1A1KDM4EGAASMN1; SMN2
SCHEMBL10221682 0.76 ALDH1A1 (0.50) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL16011602 0.72 L3MBTL1 (0.44) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL31474164 0.71 L3MBTL1 (0.41) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL5343234 0.70 KDM4E (0.45) L3MBTL1ALDH1A1KDM4EACHEMMP1
SCHEMBL13147606 0.69 L3MBTL1 (0.46) L3MBTL1ALDH1A1KDM4EPLA2G4AACHE
SCHEMBL31661354 0.69 KDM4E (0.38) L3MBTL1ALDH1A1KDM4ESMN1; SMN2GRM4
SCHEMBL292888 0.69
SCHEMBL9568973 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556123-A1 Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-18 EP disclosed