Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569108 | 0.86 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1CYP19A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7378135 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BALDH1A1CYP19A1CYP1A2 | |
| SCHEMBL31491511 | 0.80 | CCR5 (0.41) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL3887654 | 0.77 | CA12 (0.42) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL4420367 | 0.76 | EPHX1 (0.57) | EPHX1PKMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5985597 | 0.76 | CYP1A2 (0.38) | CYP1A2EPHX1PKMSLC6A2SLC6A4 | |
| SCHEMBL31491510 | 0.76 | NPC1 (0.44) | CYP2D6SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL146771 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1CYP19A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30185866 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1CYP19A1EPHX1 | |
| SCHEMBL28696042 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1CYP19A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565450-A1 | Use of peptide derivatives for the manufacture of medicaments inhibiting endopeptidases 24.15 and 24.16 | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-10-13 | — | — | EP | disclosed |