Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7378135 | 0.98 | MTNR1A (0.45) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL9569107 | 0.86 | MTNR1A (0.45) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL3887656 | 0.78 | CA12 (0.44) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL28141976 | 0.74 | SCN4A (0.52) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL2820605 | 0.74 | TAAR1 (0.44) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL146771 | 0.73 | MTNR1A (0.55) | MTNR1AMTNR1BCYP1A2EPHX1ACP3 | |
| SCHEMBL297993 | 0.72 | EPHX1 (0.43) | MTNR1AMTNR1BCYP1A2PKMSMN1; SMN2 | |
| SCHEMBL8885808 | 0.72 | POLB (0.38) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL11376402 | 0.72 | MTNR1A (0.45) | MTNR1AMTNR1BCYP1A2CYP2D6PKM | |
| SCHEMBL28696042 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BEPHX1ACP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565450-A1 | Use of peptide derivatives for the manufacture of medicaments inhibiting endopeptidases 24.15 and 24.16 | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-10-13 | — | — | EP | disclosed |