Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 14/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 14/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569164 | 0.89 | STAT3 (0.41) | STAT3TOP1MAPTTOP2ATOP2B | |
| SCHEMBL9569181 | 0.89 | STAT3 (0.38) | STAT3TOP1MAPTTOP2ATOP2B | |
| SCHEMBL9569169 | 0.88 | TOP1 (0.51) | STAT3TOP1TOP2ATOP2B | |
| SCHEMBL9560449 | 0.85 | TOP1 (0.39) | STAT3TOP1TOP2A | |
| SCHEMBL9569171 | 0.84 | TOP2A (0.51) | TOP1TOP2ATOP2B | |
| SCHEMBL9560421 | 0.82 | TOP1 (0.40) | STAT3TOP1TOP2ATOP2B | |
| SCHEMBL9513057 | 0.80 | TOP1 (0.41) | STAT3TOP1TOP2ATOP2B | |
| SCHEMBL9569144 | 0.79 | STAT3 (0.40) | STAT3TOP1MAPT | |
| SCHEMBL9569160 | 0.78 | TOP1 (0.48) | STAT3TOP1TOP2ATOP2B | |
| SCHEMBL9560484 | 0.78 | TOP1 (0.41) | STAT3TOP1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |